Antimicrobial effect of green synthesized silver nanoparticles (AgNPs) against multidrug resistant Pseudomonas aeruginosa

Abstract

Significant increase of mortality, morbidity and cost related to treatment caused by multidrug resistant (MDR) bacteria. Researchers are shifting towards nanoparticles in general and silver nano particles (AgNPs) in particular to solve the problem of emergence of MDR bacteria. Hence, AgNPs were produced by green synthesis method using green tea leaves Camellia sinensis, and were characterized by using UV spectroscopy,Fourier-Transform Infrared (FTIR) Spectroscopy,Particle Size Analyzer (PSA), Scanning Electron Microscope (SEM), and Energy Dispersive Spectroscopic (EDS). The antibacterial activity of the synthesized AgNPs were examined against Multidrug Resistant (MDR) bacteria of clinical importance(Pseudomonas aeruginosa) by means of Agar well diffusion, it was determined that AgNPs has a synergetic effect against P aeruginosa, which makes it a promising choice for use in drug products that may aid in prohibit spreading the MDR bacteria in various medical environments.