Evaluation of the effect of chamomile on salivary gland tissue in female diabetic rats

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Rasha Muzahem Hate, Hadeel Jabar Neama Almuosw

Abstract

Chamomile is considered one of the most popular medicinal herbs that are used as an antioxidant, anti-inflammatory, and a mild astringent drug, as well as used to treat asthma and some respiratory diseases. This study was designed to evaluate the effect of chamomile extract on the histological composition of some types of salivary glands of female diabetic rats, as it was used in this experiment ( 40) An adult female of white rats and her average weight (200-250 gm) was divided into four groups and the groups were equal in number, as each group included (10 rats) as follows : Control group (G1) This group was given only standard diet and distilled water for the duration of the experiment. Group G2: where I dosed rats with aqueous extract of chamomile at a concentration of 10 mg / 100 ml distilled water.
Group G3: In this group, diabetes was developed by injecting alloxan at a concentration of 180 mg / kg in peritoneum.Group G4: where the rats were dosed with aqueous extract of chamomile at a concentration of 10 mg / 100 ml distilled water after diabetes was induced by injecting alloxan 180 mg / kg in periton, and after five weeks the animals were sacrificed, salivary glands extracted and preserved in formalin, then tissue sections were prepared, Histological sections taken from the salivary glands in this group are close in shape and arrangement With the control group, when examining the sections of the diabetic group, the results showed that there are many changes in their histological structure, there is a clear effect on the structure of the cells. In conclusion : chamomile has a preventive and therapeutic effect on the disorders caused by diabetes through its antioxidant and inflammatory effect .

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Hadeel Jabar Neama Almuosw, R. M. H. . (2021). Evaluation of the effect of chamomile on salivary gland tissue in female diabetic rats. Annals of the Romanian Society for Cell Biology, 25(6), 2513–2523. Retrieved from https://annalsofrscb.ro/index.php/journal/article/view/5865
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