Antimicrobial activity of silver nanoparticles synthesised using Solanum Xanthocarpum extract against oral microbes

Abstract

Introduction In the branch of nanotechnology, the synthesis of nanoparticles and their development play a significant role because of their wide applications. They are used as antimicrobial agents and prevent the development of multidrug resistant bacteria.All parts of Solanum xanthocarpum plant, including the stem, flowers, fruits and roots have proved to have medicinal properties. Aim This study aimed to evaluate antimicrobial activity of silver nanoparticles synthesised using Solanum Xanthocarpum extract against oral microbes. Materials and Methods For this study about 25 grams of dried fruit powder of Solanum Xanthocarpum was mixed with 250 ml of water, placed in a rotating shaker at room temperature for 48 hours,filtered, air dried in room temperature and stored at 4 degree C. 25 ml of plant filtrate was added into 225 ml of aqueous solution of 1mM silver nitrate for reduction of silver nitrate into Ag+ ions and kept at room temperature for 24 hours in a rotating shaker at 28degree C. Results Solanum xanthocarpum induced with silver nanoparticles showed good antibacterial activity against oral pathogens. Conclusion The use of fruits for the synthesis of silver nanoparticles has many advantages such as, ease with which the process can be scaled up, economic viability and to obtain smaller particle size. Clinical Significance The capability of other plant parts such as fruit and root as a capping and reducing agent is not tested and not well defined.In the present study, it was found that fruits were a good source for the synthesis of silver nanoparticles.