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IntroductionThe incidence of Cerebrovascular accidents (CVA) is on the rise. Early diagnosis of electrolyte and other biochemical imbalances can reduce mortality. The comparison in these biochemical parameters in different types of stroke i.e. ischaemic and hemorrhagic is necessary to guide therapy but the studies are limited. Aim: This study will be conducted to assess and compare biochemical parameters like blood sugar level, urea, serum creatinine, Cr, Na, K, Ca, Mg, Phosphorus, lipid profile, CPK-MB, and Trop-I in patients of ischaemic and hemorrhagic stroke. Our study will build on the existing evidence and also give region-specific insights. Materials and methods:This retrospective study was conducted on the data of 100 patients, 50 of whom presented with acute ischaemic stroke and the rest 50 patients with hemorrhagic stroke in the emergency department of a tertiary care institute. Result: The mean urea and creatinine levels were within the normal range in patients of hemorrhagic stroke as well as ischaemic stroke and no significant difference was present between both groups.The mean sodium levels were decreased in both groups with no significant difference between groups. The mean potassium levels were decreased in patients of hemorrhagic stroke. The difference was significant (p=0.003). Hypocalcemia was present in patients of both groups. Magnesium and phosphorus levels were normal in both groups.Significant difference in calcium, magnesium, and phosphorus levels in both groups are missing. Conclusion: To conclude, we found that, blood sugar levels are raised in stroke patients. Diabetes Mellitus type II, Hypertension, Ischaemic heart disease, past history of CVA are some of the common risk factors.