Effects of Cinnamomum Zeylanicum on Hypergly-Caemia: A Qualitative Meta-Analysis

Abstract

Background & aims: This paper aims to impart a precise synopsis of the possible medicinal advantages of Cinnamomumzeylanicum (CZ) on hyperglycaemia for diabetic patients. Besides, the target is to establish statistical significance across studies that might have conflicting results. Methods: A systematic literature search was carried out in the following databases: PubMed, Science direct, Google Scholar in range time studies from 2010 - 2020. A qualitative meta-analysis of research analysing the impact of CZ extracts on the hyperglycaemia condition in a patient. Results: 14 studies were included in qualitative meta-analysis. The in vitro study showed that cinnamaldehyde in CZ helped the translocation of Glucose Transporter type-4 (GLUT4) to the membrane cell in diabetic rats. In vivo study showed that the treatment of CZ in diabetic rats with small dose in longer durations helped to reduce the Fasting Blood Glucose (FBG). Most of the studies from human trials showed the daily supplementation of 3 grams of CZ powder for eight weeks significantly reduced the FBG. Conclusion: The extract of CZ is useful to reduce the blood glucose level in different forms. It shows an improvement in glycaemic control and increases the action of insulin in the β-cell of pancreas to produce more insulin.