Effect of Ascorbic Acid Supplement on Hematological Parameters and some enzyme activities of Male Rabbits

Abstract

      The water-soluble micronutrient Ascorbic (vitamin C) is an essential for several biological activities. Ascorbic acid has a long history of usage in conventional processes that regulate the production of free radicals with antioxidant effects. Free radical levels in cancer cells have been documented to be high. The research aimed at studying hematological of the adult male rabbits. ascorbic acid (40mg/kg/BW/day for 12 weeks). The influence of ascorbic acid at the termination of a 12 week clinical cycle on complete counts of erythrocytes (CBR), hemoglobin (HB), cell-packed volume (PCV), total WBC, MCV, MCHC, mean plasma glutathione-s-transferease (GST), acetyl cholinesterase (AChE), and thiobarbituric acid-reactive substances (TBRS). Ascorbic acid therapy resulted in a substantial improvement (P<0.05) in RBC and WBC, while Hb, PCV, MCV, MCH, MCHC, GSH, AChE behavior were not changed in contrast with regulation. Compared to control community, the TBARS are considerably decreased (P<0.05). This search concludes the addition of a vitamin C supply to food will boost anemia and suppress free radicals in adult male rabbits for a long period.