Indocyanine Green-Mediated Photodynamic Therapy as Adjuvant to Non-Surgical Periodontal Treatment in Chronic Periodontitis Patients: A Clinical and Microbiological Study

Abstract

Aim: To evaluate the efficacy of indocyanine green-mediated photodynamic therapy as an adjunctive therapy to scaling and root planing by evaluating clinical and microbiological parameters in the treatment of chronic periodontitis.

Materials and methods: Thirty-foursystemically healthy patients were screened. In this split-mouth study, contralateral sites were allotted to Group 1 (Scaling and root planing) and Group 2 (Scaling and root planing with photodynamic therapy). Indocyanine green dye (Aurogreen™) and diode laser at 810nm were used for antibacterial photodynamic therapy. Subgingival plaque samples were obtained from the patients at baseline and three months after treatment. Clinical parameters (PPD, CAL, PI, GI and mSBI) were recorded both at baseline and after three months. The plaque samples were then subjected to microbial culture on blood agar and colony forming units were counted.

Statistical analysis:Results were statistically analysed using Mann Whitney test and Wilcoxon Signed Rank Test.

Results: All clinical and microbiological parameters showed statistically significant reduction following Phase I therapy after a period of three months in both groups. There was also a statistically significant improvement in all parameters in Group 2 (SRP+PDT) when compared to Group 1 (SRP) at the end of the treatment period.

Conclusion: Indocyanine green-mediated photodynamic therapy has a significant role as an adjuvant in the non-surgical management of chronic periodontitis and is shown to be better than SRP alone.