Research Progress of Hibiscus Sabdariffa Medical Plant as Infertility Agents on Male Rabbits

Abstract

Medical plants are characterized by physiological active principles that have been utilized in traditional medicine years ago in treatment of different diseases. Previous studies indicated that Hibiscus sabdariffa has ethno-medical and ethno-veterinary characteristics; however, the relationship between and male reproductive hormones levels has not been clearly demonstrated. The objective of the current work was to examine the impact of 30% concentration H. sabdariffa extract on reproductive hormones and histological effects of the testis of adult male rabbits.Crude extract of blooms of Hibiscus rosasinensis has been demonstrated that there was definite antifertility effect of this extract in causing degenerative changes in the germinal epithelium of male rabbits. Effect of H. sabdariffa on basal levels of testosterone, follicle stimulating hormone (FSH) and luteinizing hormone (LH) was studied using post pubertal healthy male rabbits. Calyx extract of H. sabdariffa at a dose of 300 mg/kg reduced reproductive hormones in experimental rabbits. In conclusion, calyx extract of H. sabdariffa can have negative impact on male reproductive hormones in rabbits and the histological formation of the testicle.