Complex Therapy of Comorbid Transsyndromal Hypotrophy and Anemia in Calves.

Abstract

Nowadays diseases of young animals are widespread in animal husbandry.A significant amount of them are abnormalities of blood system.Anemias arethe most common diseases of the blood systemin veterinary medicine. Anemia is associated with unfavorable conditionsof keeping and feeding animals, the birth and development of morphological and functional immature hypotropicyoung animals. Taking into consideration the deterioration of the local environment, an increase in cases of mass anemia among young cattle is to be expected. Thearticlecontainsinvestigation of hypochromic microcytic anemia (HMA), a disease characterized by a violation of hemoglobin synthesis due to iron deficiency. Iron deficiency anemia is diagnosed in 100% of calves with various forms of hypotrophy. The material for the study was the calves of the Holstein-Frisian breed from birth to 14 days. In the first series of studies, a group of clinically healthy calves and a group of hypertrophic calves with hypochromic microcytic anemia were formed. Each group contains 16 heads of newborn calves. Hematological studies in healthy calvesin the age aspect and in the future are described, theobtained results were compared with the blood parameters of hypertrophic calves diagnosed with comorbid anemia. In the second series of experiments, calves with prenatal hypotrophy and comorbid pathology were divided into control (intact) and experimental groups. Each group contains 8 heads of calves which were similar in age, body weight and were kept in the same conditions of maintenance; feeding and care. The article describes a comprehensive therapeutic method. A single fortification with eleovit solution at a dose of 2 ml, a Ringer-Locke solution at a dose of 100 ml, a 10% solution of carnitine chloride at a dose of 100 mg / kg were used to restore erythropoietic function of the red bone marrow and increase the reactivity of the hypertrophic calves` organisms included in the experimental group with diagnosed anemia. Actovegin at a dose of 5 mg/kg was usedonce for 10 days daily to stimulate hematopoiesis to stimulate hematopoiesis. Taurine at a dose of 100 mg combined with colostrum and milk for the first 14 days of calf`s life was used per os to prevent stressdisadaptation. Restoring the iron content in the body normalizes phagocytosis, increases the activity of natural killer cells and the bactericidal ability of serum sufficient for synthesis of complement and lysozyme.Thus, the optimization of iron and protein metabolism in the functioning of factors of non-specific protection, cellular and human immunity leads to the restoration of the immune status of newly born hypertrophic calves with hypochromic microcytic anemia. As a result of the restoration of hematopoiesis and metabolic processes, body weight and average daily weight gain in the calves of the experimental group are normalized. At the end of the study, the animals had parameterscorresponding to their age and breeds.