Using The Platinum as an Ion Association Complex in the Indirect Determination of Microgram Quantities of Some Alkaloids and Pharmaceutical Compounds by GET-AAS

Abstract

Determination of microgram quantities of some alkaloids and pharmaceutical compounds such as Berberine (BRB) Narcotine (NAR) and Cinconine (CNC) using PtI42- ion. The method involves the formation of ion - association - Pt - complexes with these alkaloids and subsequent solvent extraction of the complexes produced followed by determination of the platinum concentration after inject 20 ul from the organic layer into the GET-AAS.

The optimum conditions such as the concentration of the PtI42- ion, pH-value of the complexes formation, kinds of organic extraction solvents, volume and number of extractions as well as time of the consuming reaction were studied.
The linear dynamic range, precision, Accuracy, detection limits and relative standard deviation (n=5) have been computed for each alkaloid investigated.

The results achieved were satisfied comparing with a previous one using different metal.