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Laboratory tests use percentage of glycated hemoglobin (% HbA1c) to check diabetes control. Worldwide, Diabetes is the most dramatic disease of all current human health problems. The objectivity of this study is to assess the relationship amongst hemoglobin which is glycated and levels of depression in volunteer participants . 90 participants were divided into three categories according to their glycated hemoglobin measured level (Hb A1c) as follows: normal (4 - 5.6 % ) , risky (5.7 - 6.4 %) , and DM ( 6.5 ≥ % ) .participants were assessed using the Likert depression scale. The evidence for the relation between high Hb A1c and depression was clear. A high significant level of mild depression was observed among the diabetic (6.5 ≥ % ) category 44 (71.0%) of the rest. DM category also showed 14 cases of moderate depression 2(3.2%) , while not found in the rest (0.0%).Thus, it was concluded that high glucose levels and depression are interrelated .