Pharmacogenetic Aspects of Drug Resistance in Rheumatoid Arthritis
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Abstract
Glucocorticoids are essential steroid hormones involved in the regulation of adaptation to stress, carbohydrate, protein, fat, calcium and bone metabolism, immune function, growth and behavior regulation. To date, more than 15 different GR mutations have been identified that cause glucocorticoid resistance. This review provides information on the nature of the genes responsible for pharmacoresistance in patients with rheumatoid arthritis to glucocorticoids.
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Sultonov I. I., Ziyadullaev Sh. Kh., Ruzybakieva M. R., Kireev V. V., Aripova T. U., Suyarov A. A. (2021). Pharmacogenetic Aspects of Drug Resistance in Rheumatoid Arthritis. Annals of the Romanian Society for Cell Biology, 4147–4150. Retrieved from https://annalsofrscb.ro/index.php/journal/article/view/1904
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