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Aim of study: Determine the relationship between the parasitic infection of T. gondii and Programmed cell death-1 (PD-1), TGF- ß and IL-10 during abortion.
Materials/Methods: One hundred consecutive samples after abortion were collected. The placental tissue samples were put in formalin for immunohistochemistry technique.
Result the result of this study reveals that Residence did not have a relation with the presence or absence of Toxoplasmosis (P>0.05), age was significantly different between Toxoplasmosis groups (P<0.05), Number of abortions was not significantly different between the Toxoplasmosis group (P>0.05), PDL-1, IL-10, and TGF-β levels and their relationship during infection is significant (P<0.05).Conclusion the PDL-1, IL-10, and TGF-β levels could be a candidate as a biomarker for the pathological effect of Toxoplasma.gondiin during pregnancy.