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Hand sanitizers are available in the form of liquid, gel or foam used to decrease infectious agents on the hands. This way of sanitation which doesn’t require water or any other material. This is the best way of killing organisms and they are portable.They are made of alcohol and hence they evaporate once they are placed on hands. Commercially prepared sanitizers have aloe vera gel which is an important ingredient in prevention of skin dryness.The hand sanitizers have a great impact in the reduction of student absenteeism from illness by 20%.It kills germs bacteria,virus, and interrupt the transmission of flu like diseases. This method of hand sanitation is the best way of killing microorganisms on a larger scale. It’s said that sanitizers kill 99% of microorganisms. But sanitizers are good bactericidal agents rather than antimicrobial agents. The new developments in the sanitizers include the addition of aloevera gel. This prevents the hands from dryness. The aim of the research is to study the recent developments on hand sanitizers.