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Objective wastoresearch the effect of high-energy laser therapy in shoulder impingement syndrome versus phonophoresis. Study design was A provisional, randomized, pre-post-test, controlled experiment. Setting Cleopatra Hospital - Egypt ambulatory clinic. The trial was carried out betweenJuly 2020 and January 2021. Participants; Forty diagnosed Patients with 1 - 2 stage impingement pain syndrome was divided randomly into two equal groups. Interventions; Group (A) underwenta program of Neodymium-yttrium Aluminum Garnet Laser 1064 nm Wave Length Hiro 3, high intensity pulsated laser 8 W, 12 J/cm2 dose and 10000 J of Total energy maximum was applied for 15 minutes and 150 'us' single impuls, 760 mj, two sessions a week for one and half month in addition to exercise.Group (B) In addition to an exercise phonophoresis was obtained with sodium diclofenac. Major outcomes measurement; Scale visual analog (VAS), electro goniometer, Ultrasonography. A statistically significant reduction was observed in VAS score, and improvement of mobility of shoulder in laser group compared with phonophoresis group (p< 0.05). In Conclusion. In impingement syndrome, high-level laser therapy contributed to an increased shoulder mobility.