A Study Protocol on The Efficacy of Fluticasone Versus Bharangi (Clerodendrom Serratum Linn) Arka (Aqueous Extract) Nasal Spray In Pratishyaya (Chronic Allergic Rhinitis) In Children

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Dr. Deepthi Balakrishnan, Dr. Renu Rathi, Dr. Bharath Rathi, Dr. Monika

Abstract

The pervasiveness of Allergic rhinitis among children is high while comparing other inflammatory diseases. Even though it doesn’t have a direct impact on their well-being, it is the villain of the piece interrupting their healthy growth. A closer look at school-going children reveals the fact that Allergic rhinitis is one of the most visible symptoms that disturbs their cycle of life. Fluticasone nasal spray considered as the Gold Standard in COPD (Chronic Obstructive Pulmonary Disease) is the first line treatment method usually prescribed in this ailment. The disease Pratishyaya mentioned in classical Ayurveda texts exhibits features analogous to Allergic rhinitis. Arkaprakasha, serves as the principal testament to the sanative value of Bharangi Arka in Pratishyaya. The Arka prepared from the root of Bharangi has pharmacological effects adequate to pacify the disease. This study plans to evaluate the equivalent efficacy of Bharangi Arka and Fluticasone in Allergic rhinitis. Both of the drugs are administered in the form of nasal sprays since they can be applied more conveniently and easily on the school going group. For the study, 84 children from the age group of 4-14 years with Pratishyaya is selected arbitrarily fulfilling the inclusion criteria and is categorized into two groups. The choice between the nasal sprays is be made by Double- blind method and the assessment is done based on TNSS (Total Nasal Symptom Scoring) within a duration of 28 days. If Bharangi Arka is found to have a fruitful effect, it could foster further research with revamped Ayurveda formulations

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Dr. Deepthi Balakrishnan, Dr. Renu Rathi, Dr. Bharath Rathi, Dr. Monika. (2024). A Study Protocol on The Efficacy of Fluticasone Versus Bharangi (Clerodendrom Serratum Linn) Arka (Aqueous Extract) Nasal Spray In Pratishyaya (Chronic Allergic Rhinitis) In Children. Annals of the Romanian Society for Cell Biology, 28(01), 61–71. Retrieved from https://annalsofrscb.ro/index.php/journal/article/view/11790
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