Study on the Biochemical Alterations in People with Human Immunodeficiency Virus Infection both before and after Antiretroviral Therapy

Abstract

Biochemical changes in people infected with the human immunodeficiency virus before and after treatment with antiretroviral drugs are described in this study. Antiretroviral therapy (ART) improves the health and lifespan of people living with HIV-1, but it also raises the danger of metabolic abnormalities in some patients.This study consisted a group of people with HIV who had never taken ART before for a few months to see if their nutrition or the way the medicine worked, changed. The goal of study is to evaluate blood counts and other biochemical markers in HIV patients receiving antiretroviral medication. A regular screening of HIV on antiretroviral medication is necessary to identify individuals in need of nutritional care because the improvement in nutritional status appears to be a glacial. A total of 9,418 HIV patients with ART failure among 2004 and 2016 were included in this retrospective analysis. Age, CD4 count, viral load, hyperglycemia, creatinine & triglyceride levels were acquired from EHR databases to monitor patients' progress.