Clinical Evaluation of Repeat Peroral Endoscopic Myotomy for Achalasia

Abstract

Aim:The goals of this research are to evaluate the efficacy, safety, and feasibility of repeating the peroral endoscopic myotomy (Re-POEM) procedure for achalasia patients.

Methods:Between February 2018 and August 2020, we performed Re-POEM on ten patients with achalasia whose first POEM attempt had failed. What kind of complications occurred, how long patients stayed in the hospital after surgery, how long patients waited for results, how long patients waited for results, how long patients waited for results, how long patients waited for results, how long patients waited for When you say "follow-up time," what exactly do you have in mind? And/or additional criteria? We statistically assessed the results of our observations of add).

Results:All Re-POEM surgeries were technically successful 100% of the time. There were no significant variations in operational time, postoperative fasting time, postoperative hospital stays, or total hospitalisation expense when comparing the current POEM to the original POEM. There were no perforations, pleural effusions, or gas-related complications in either procedure, and the rates of mucosal injury, chest discomfort, fever, and delayed bleeding were similar (P>0.05). All patients' Eckardt scores were less than 3 throughout the median 8.5-month (5-28-month) follow-up after Re-POEM. Three individuals developed clinically associated gastroesophageal reflux disease (GERD), with one instance showing reflux esophagitis by gastroscopy. The symptom score ranged from 1.4.

Conclusions:When initial POEM has failed and a patient presents with persistent or recurrent dysphagia, re-POEM is a practical, safe, and successful option.