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In December 2019, an original virus of corona known as Covid19 was determined to be the root of the SARS2 sickness in Wuhan, China, resulting pneumonia, failure of the majority of respiratory systems, and follow by death. There is no denying Although Covid19 is typically thought of as an infectious respiratory disease with a number of respiratory problems that can lead to mortality overseas, it may also affect the urinary and digestive systems as evidenced by symptoms and histological damage to the kidney, nervous tissue and gastrointestinal tract. Previous studies found corona virus RNA2 in the feces of asymptomatic individuals, in addition to infiltration of lymphocytes and plasma cells through the connective tissue of interstitial area of lamina properia in mucosa layer, as well as degeneration and shedding of epithelial layer in mucosa of most sections of the alimentary canal. Presence of evidence of nervous system involvement the presence of ACE2 receptors has been linked to viral tropism in the kidney and alimentary tract. In this study, we look at the most important microscopical and histopathological changes associated with this new illness.