Tubular Bone Marrow Electrolytes

Abstract

Determination of bone marrow ions is of certain difficulty because of the reliability of the obtained results. But under strict conditions it is possible. Bone marrow ion structure has not practically been studied by anyone. This is due to the fact that, for research, bone marrow is usually obtained by puncture of the iliac crest or puncture of the sternum. As a rule, during this procedure a quantity of blood that distorts the indicators gets to punctate. Recently cell therapy associated with the therapeutic effect of stem cells has been actively studied and introduced into medical practice. One of the sources of stem cells is bone marrow. The content of ions in biological tissue, their constant quantitative structure, provide a certain functional state of cells, therefore, the study of bone marrow electrolytes is important. In this work, for the first time, quantitative indicators of bone marrow ions are determined, a comparative analysis of ions is carried out depending on the place of receipt, electrolyte norms for tubular bone marrow are determined. Quantitative indicators of bone marrow electrolytes of the tubular bones were established: K 4.1 ± 0.12 mmol / l; Na 130.5 ± 4.3 mmol / L; Ca 1.37 ± 0.07 mmol / l; Cl 131 ± 2.4 mmol / l. Studying electrolytes and conditions surrounding the stem cells in the bone marrow it is possible to create a medium for the cultivation of stem cells as close as possible to natural ones.