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Over the last few years, there has been a rise in public awareness regarding obstructive sleep apnea (OSA). Patients who suffer from this disease are at a risk for other diseases, road traffic accidents and higher mortality. Patients with sleep disordered breathing experience hypersomnia, morning headaches, nausea, and restless sleep at night with frequent arousals. However, often their signs and symptoms are overlooked and neglected due to incognizance on part of the dentists. As a result, despite its high prevalence, it is frequently misdiagnosed. A normally appearing snoring can lead to progressive form of obstructive sleep apnea which can result in medical conditions like polycythemia and right sided heart failure. A greater understanding of these connections would improve skills in offering a more holistic approach to care for patients. Although continuous positive airway pressure (CPAP) is the first line of treatment for sleep apnea, mandibular advancement devices play a significant role, requiring dentists to have a strong grasp of occlusion, TMD, and removable appliance treatment. This article will provide an overview of oral appliances that can be used for the treatment of this serious disorder.