Antifungal Susceptibility Profile of Dermatophytes in a Tertiary Care Hospital

Abstract

The main aim of the current research was to detect the species level of dermatophytes. Primary Isolation and speciation of dermatophytes will help us to know the source of infection. Antifungal susceptibility testing of dermatophytes will play a crucial role in understanding a sensitivity patterns and failed or successful in treatment. In the present study 180 clinical suspicions collected from outpatient department of dermatology. The collected clinical suspicions were processed direct microscopy and inoculated onto dermatophyte test medium, Sabouraud dextrose agar containing cycloheximide, potato dextrose agar for isolation. The identified fungal isolates were further tested with four antifungal agents by using two antifungal susceptibility testing methods. In this study out of 180 clinical cases tinea corporis 108(60%) was the most predominant condition followed by tinea unguium 54 (30%). Among 180 samples 96 (53.3%) yielded the growth of dermatophytes in which 45 (46.8%) were Trichophytonrubrum followed by 29 (30.2%)Trichophyton mentagrophytes. Itraconazole showed the highest rate of sensitivity followed by griseofulvin in both methods.