Assessment of the Level of Interleukin-10 in Patients with COVID-19

Abstract

The current study aimed to assess the level ofInterleukin-10 among Covid-19 patients by using the ELISA technique. For this purpose, (100) serum samples were collected from patients infected with Covid-19 disease in the city of Kirkuk for the period from February 20, 2021 to July 8, 2021, with ages ranging from 22 to 93 years, fifty males and fifty females.The patients were divided according to the severity of the disease into three groups, the first group had mild symptoms (19%), the second group had moderate severity (41%), and the third group was severe (40%). The results of the study showed a significant increase in the levels of interleukin-10 (73 ± 8.2 pg/ml) among Covid-19 patients compared to the control group (P.Valeu ≤ 0.05).Interleukin-10 also recorded the highest level in severe cases (121.1 ± 3.11 pg/ml) compared to moderate and mild cases (P.Valeu ≤ 0.05).Also, the level of interleukin-10 increased significantly among Covid-19 patients with diabetes, and the highest increase was recorded in severe cases, where it was (142.9 ± 7.27 pg/ml, P.Valeu ≤ 0.05).