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We present a case of a 54- years old female patient with the diagnosis of lung adenocarcinoma and cutaneous metastases, which come a long way from the initial symptoms to definitive diagnosis. Adenocarcinoma is the predominant histological subtype of the non-small cell lung cancer. The case showed how important it is to remember that skin metastasises could be the first symptoms of the cancer. The physicans (general practice and dermatologists) should be aware of the phenomenon of the atypical skin lesions. Every case should be evaluated with biopsy for further possible research and supportive treatments. We would like emphasize the importance of a multidisciplinary approach and of its role in individualizing the diagnostic and treatment.