Study of the Effect of Portunuspelagicus (Linnaeus 1758) on Fat Discoloration in Male Rabbits Exposed to Oxidative Stress

Abstract

The present study aimed to investigate the effects of Portunuspelagicus powder (Linnaeus, 1758) on the lipid profile such as: Total Cholesterol (TC), Triglycerides (TG), and High-Density Lipoprotein (HDL-HD lipoprotein). Low density lipoprotein (LDL-C), very low-density lipoprotein for cholesterol, Very low-density lipoprotein (VLDL-C), the antioxidant enzyme glutathione (GSH), and Malondialdehyde (MDA).In domestic male rabbits exposed to oxidative stress with hydrogen peroxide H2O2 at a concentration of (0.5%) in drinking water throughout the adult experiment period (60) days, the most effective dose of blue crab powder was determined through preliminary experiments, and it was (10 g / kg) of The bush for adult rabbits was divided randomly into (6) groups, since each group included (5) rabbits and as (G1) the control group and (G2) the effective dose group for crab powder alone and (G3) the hydrogen peroxide group H2O2 alone and (G4) the crab powder group (5) g / kg of feed + H2O2 and (G5) the crab powder group (10) g / kg of feed + H2O2 and (G6) group of crab powder (15) g / kg of feed + H2O2.

The results of this study showed: that the treatment of animals with blue crab powder alone led to a significant decrease in MDA, TC, TG, LDL-C, and VLDL-C. While there was a significant increase in GSH, HDL-C compared to control.The treatment of animals with hydrogen peroxide alone led to a significant decrease in the concentrations of GSH, HDL-C, and VLDL-C compared to the control. Whereas, this treatment led to a significant increase in MDA, TC, TG, and LDL-C compared to the control group. The treatment of crab powder (5) g / kg of feed + H2O2 led to a significant decrease in the concentrations of MDA, TC, TG, HDL-C, LDL-C, VLDL-C compared to the control group.While it led to a significant increase in the concentration of GSH, and the treatment of animals with sea crab powder (10) g / kg of feed + H2O2 led to a significant decrease in the concentrations of MDA, TC, TG, LDL-C, VLDL-C compared to the control. While there was a significant increase in GSH, HDL-C. The treatment of marine crab powder (15) g / kg of feed + H2O2 led to a significant decrease in the concentration of MDA, TC, TG, LDL-C, VLDL-C, as compared to the control. While it led to a significant increase in the concentrations of GSH and HDL-C.