Study of Nitric Oxide and Some Hormonal Parameters in Hypertensive Men

Abstract

We examined the associate of some sex steroid and reproductive hormones including ( testosterone(T) , estradiol (E2) and prolactin (PRL) with nitric oxide (NO)  in hypertensive men.The sample of this study divided  into three main groups (30/group ) as following : 1st group (40-45) years  , 2nd groups  (50-55) years and 3rd group ( 60-65) years  , each of these three main groups divided into two subgroups: 1st subgroup ( 15 normotensive men ) , 2nd subgroup (15 hypertensive men ) . Results revealed : testosterone levels  reduced  significantly  (p ≤ 0.05)  for all samples in different subgroups and groups during  hypertension  . Both estradiol  (E₂) and prolactin (PRL) increased  significantly (p ≤ 0.05) for all samples in different subgroups and groups . Nitric oxide reduced significantly (p ≤ 0.05)  for all samples in different subgroups and main groups ( except the third subgroup and the third group in hypertensive)  . These findings are inconsistent with the hypothesis that nitric oxide be associated  with low testosterone highestradiol and prolactin levels and hypertension .