Evaluation of the Relationship between Maternal Serum Vitamin D Level and Abortion in Patients Referred to Ali Ibn Abitaleb Hospital in Zahedan in 2018

Abstract

Background and Aim: Due to the increasing prevalence of vitamin D deficiency, there is concern about the effects of the high prevalence of vitamin D deficiency in the entire population of the world, including pregnant women. Therefore, the aim of this study was to determine the relationship between maternal serum vitamin D levels and abortion in patients referred to Ali Ibn Abitaleb Hospital in Zahedan.

Materials and Methods: In this case-control study, 50 mothers who were admitted to the gynecology ward of Ali Ibn Abitaleb Hospital in Zahedan due to abortion were included in the case group, and 50 healthy pregnant women with normal gestational age and no history of abortion were considered as controls.Serum levels of vitamin D less than 10 ng/ml were considered as vitamin D deficiency and 10 to 30 ng/ml were considered as inadequate levels. Then, information such as maternal vitamin D level as the main target and maternal age, paternal age, and fetal age as the secondary target of the study were determined.

Results: The subjects were in the age range of 17 to 35 years with an average of 26.27 ± 4.84 years. The results showed that the frequency of severe vitamin D deficiency was 34% in the case group and 12% in the control group.Based on the results of this study, it was found that the mean serum level of vitamin D and gestational age in the group of mothers with abortion were significantly lower than the control group (P <0.05).

Discussion and Conclusion: In our study, it was found that mothers with abortions have low levels of vitamin D. Also, the frequency of severe deficiencies in these people was higher than those without abortion, and vitamin D deficiency in people under 30 years of age was more important than people over 30 years of age; In addition, the levels of this vitamin was not affected by gestational age.