Preliminary Outcomes and Safety of Menopausal Symptoms Treatment using Cannabis-containing Suksaiyat Formulation based on Thai Traditional Medicine Wisdom

Abstract

The objectives of this study were to study the cannabis-containing Suksaiyat formulation based on Thai traditional medicine wisdom and to study the preliminary outcomes and safety of menopausal symptoms treatment using cannabis-containing Suksaiyat formulation. This study was a qualitative research. The data were collected using in-depth interview, observation and focus group discussion from Thai Traditional Medical Cannabis Clinic, Phanatnikhom Hospital, ChonBuri Province, where Special Access Scheme (SAS) have been used as individual patient treatment. Data triangulation was conducted and the results were presented using descriptive statistics.

       The results showed that Suksaiyat formulation listed in Vishnu's Medicine Scripture. This formulation contains 12 active ingredients with a total weight of 78 parts. The main ingredient with highest proportion is cannabis leaves, accounting for 12 parts. There were 2 groups of menopausal symptoms reported by the subjects: 1) pain in the muscles, tendons and bones. In this study, the symptoms showed improvement after 2 months of treatment. 2) neurological and circulatory symptoms included insomnia, hot flash, hot flash, loss of appetite (patients reported that these symptoms were improved within 1-2 weeks), dyspnea, weakness, irritable and vaginal dryness and atrophy. Treatment outcomes: 1) Suksaiyat is a thermal formulation with hypnotic, appetite stimulating, analgesic and anti-stress effects. Instructions: dissolve 0.5 g of this formulation in water and drink with 1 g of “Thepjit cordial”. In this study, the treatment follow-up period was 1-3 months. 2) Thepjit cordial was used as a supplementary or aqueous adjuvant. Thepjit cordial consists of 48 active ingredients and is suitable for fainting and dizziness. 3) Acupressure point massage was performed at 4-5 points and the patients were asked to refrain from injurious foods such as sticky rice, bamboo shoot, offal, liquor and beer. For the safety of menopausal symptoms treatment using Suksaiyat formulation in a period of 1-3 months, it was found that the use of Suksaiyat formulation in combination with Thepjit cordial was safe without any adverse effects.