Correlation of Endometrial Biopsy by Pipelle and Vaginal Cytology in Assessing the Type of Dysfunctional Uterine Bleeding

Abstract

To assess efficacy of vaginal cytology in diagnosing the type of dysfunctional uterine bleeding by correlating it with endometrial histopathology by pipelle. Comparing endometrial sampling and vaginal cytology in dub there is no statistically significance difference between endometrial sampling and vaginal cytology with maturation index on dub type, it was confirmed using chi square test. However, the endometrial sampling is always superior to the vaginal cytology as it helps to know detailed histology of endometrium especially the hyperplasias, atypias, any premalignant conditions espescially in perimenopausal age group. Thus vaginal cytology cannot replace the endometrial biopsy.